The Buffalo Bills and the St. Louis Rams will both be gunning for a victory on Sunday when they meet at Edward Jones Dome.
Oddsmakers currently have the Bills listed as 8½-point favorites versus the Rams, while the game's total is sitting at 43.
The Bills edged Oakland 24-23 as a 10-point favorite in Week 3. The combined score went OVER the posted over/under total (37.5).
Trent Edwards passed for 279 yards with a touchdown and an interception for Buffalo, while Marshawn Lynch rushed for 83 yards with a pair of touchdowns on 23 carries.
The Rams lost to Seattle 37-13 as an 8-point underdog in Week 3. The combined score went OVER the posted over/under total (44.5).
Marc Bulger passed for 172 yards with a touchdown for St. Louis and Stephen Jackson rushed for 66 yards on 23 carries.
Current streak:
Buffalo has won 3 straight games.
St. Louis has lost 3 straight games.
Team records:
Buffalo: 3-0 SU, 2-1 ATS
St. Louis: 0-3 SU, 0-3 ATS
Buffalo most recently:
When playing in September are 5-5
When playing on turf are 7-3
After outgaining opponent are 8-2
When playing outside the division are 6-4

St. Louis most recently:
When playing in September are 2-8
When playing on turf are 2-8
After being outgained are 1-9
When playing outside the division are 2-8
A few trends to consider:
The total has gone OVER in 5 of Buffalo's last 5 games when playing St. Louis
The total has gone UNDER in 6 of Buffalo's last 7 games on the road
Buffalo is 4-1 ATS in its last 5 games when playing St. Louis
Buffalo is 4-1 SU in its last 5 games when playing St. Louis
The total has gone OVER in 5 of St. Louis's last 5 games when playing Buffalo
The total has gone OVER in 4 of St. Louis's last 5 games
The total has gone OVER in 5 of St. Louis's last 7 games at home
St. Louis is 1-4 ATS in its last 5 games when playing Buffalo
Next up:
Buffalo at Arizona, Sunday, October 5
St. Louis at Washington, Sunday, October 12