Interleague baseball betting play is just around the corner, but a pair of major rivalries each still have another tilt on the sked tonight. Let’s make some MLB betting picks for the Cubs vs Cardinals odds and the Red Sox vs Blue Jays odds.

Red Sox vs Blue Jays odds—Jon Lester (2-4, 6.51) vs Robert Ray (1-1, 3.60), 7:10 p.m. ET
MLB odds: Red Sox -200, Blue Jays +170

You can almost hear Blue Jays odds supporters leaping off the bandwagon already after Toronto lost two of three to the Yankees last week and now stares down a sweep at the hands of the Red Sox . No-name hurler Robert Ray doesn’t exactly inspire confidence in sportsbook players tonight. He hasn’t been half bad for the Jays so far this season but his solid home outings against the White Sox and Orioles can’t possibly prepare him for the experience of pitching before a hostile crowd at Fenway. Jon Lester has struggled in baseball betting this season but he’s 17-4 all-time at Fenway and his friendly surroundings give him as good a chance as any to bounce back. Bet on the Red Sox to pull off the sweep.

Baseball betting pick: Red Sox -200

Cubs vs Cardinals odds—Sean Marshall (2-2, 4.02) vs Adam Wainwright (3-2, 3.83), 8:15 p.m. ET
MLB odds: Cubs +120, Cardinals -140

Here‘s an example of how baseball betting lines can be deceiving. The Cards are just a mild favorite at home when they’re actually a rock-solid pick tonight. Marshall has faced St. Louis twice already this season, allowing six earned runs over 11 innings. He didn’t dominate the Cards in either start and now Albert Pujols and company get a third crack at him. Wainwright’s career numbers against the Cubs aren’t that great, but a closer look at his splits shows he’s owned them from 2008-on. He dominated Chicago to the tune of 2.38 ERA and .186 batting average in ’08 and carved the Cubbies up on April 24, allowing one earned run over seven innings. The Cards look good for anyone betting sports tonight.