OffshoreInsiders.com has issued a point spread alert for the Indianapolis Colts vs. Buffalo Bills.

The best place to bet the Colts is at BetUs where they are getting 3.5. The best place to bet the Bills is at SportsBook where they are laying three-points -115.

This game is being played at the Rogers Centre in Toronto. Each team is 0-1 straight up, Indianapolis getting blown out by 20 points and the Bills by 25.

Jeff Brohm is expected to take over at QB after starter Trent Edwards leaves for the Bills. Rookie C.J. Spiller will get extensive playing time at running back.

The top sportsbook to bet the under is Just Bet Sportsbook, where the total is 37. NFL power ratings have Buffalo -2.5, so value is with Indianapolis.

The Colts have a 3-2 series lead in preseason straight up play.

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