Las Vegas betting odds are up for NFL picks and predictions the Arizona Cardinals vs. San Diego Chargers.

The bookmaker’s point spread is the Chargers laying anywhere from -9.5 at Sportsbook to as high as -11 at BetED but at +113.

Spread betting trends (all records are against the spread): Cardinals are 7-0 ATS in their last 7 games in October, 10-2 as underdog, 7-22 ATS in their last 29 road games vs. a team with a losing home record. The road team is 5-0 in the series.

Chargers are 22-8 ATS in their last 30 games as a home favorite of 3.5-10.0, 20-9-3 ATS in their last 32 games following a S.U. loss

Over/under trends: Over is 21-5 in Cardinals last 26 games after accumulating less than 250 total yards in their previous game, over 40-14 last 54 games as a road underdog.

Top expert pick on this game:  From Matt Rivers, the title says it all, an Outright or a Burial, with no in-between. It’s the game involving Arizona and San Diego. Are we looking at a Cardinal upset win and 3-1 start to the season or will the Chargers get back to .500 and take care fo business going away? Two winners in all, the 400,000* from San Diego along with a 200,000* Carolina and New Orleans. I’m up over 3 million* of profit in the last three weeks alone and that number will only grow today. Click now to purchase