NCAA football lines are up for week 3 college football betting beginning with Thursday night September 13. The big college football picks card for sports betting experts is Saturday, September 15.
| GAME | HANDICAP | ||
| Thu 9/13 | 103 | Rutgers | +8.5 1.952 |
| 04:30 PM | 104 | South Florida | -8.5 1.952 |
| GAME | HANDICAP | ||
| Fri 9/14 | 105 | Washington State | -11 1.952 |
| 06:00 PM | 106 | UNLV | +11 1.952 |
| GAME | HANDICAP | ||
| Sat 9/15 | 107 | Navy | +5.5 1.935 |
| 12:30 PM | 108 | Penn State | -5.5 1.971 |
| Sat 9/15 | 109 | Massachusetts | +45.5 1.952 |
| 12:30 PM | 110 | Michigan | -45.5 1.952 |
| Sat 9/15 | 111 | Boston College | +3.5 1.952 |
| 12:30 PM | 112 | Northwestern | -3.5 1.952 |
| Sat 9/15 | 113 | Eastern Michigan | +23.5 1.990 |
| 09:00 AM | 114 | Purdue | -23.5 1.917 |
| Sat 9/15 | 115 | No Illinois | -3 1.917 |
| 09:00 AM | 116 | Army | +3 1.990 |
| Sat 9/15 | 117 | Wake Forest | +26.5 1.952 |
| 09:00 AM | 118 | Florida State | -26.5 1.952 |
| Sat 9/15 | 119 | Connecticut | -2.5 1.952 |
| 09:30 AM | 120 | Maryland | +2.5 1.952 |
| Sat 9/15 | 121 | Texas A&M | -13 1.943 |
| 12:30 PM | 122 | SMU | +13 1.962 |
| Sat 9/15 | 123 | Virginia Tech | -10 1.917 |
| 09:00 AM | 124 | Pittsburgh U | +10 1.990 |
| Sat 9/15 | 125 | USC | -8.5 1.952 |
| 04:30 PM | 126 | Stanford | +8.5 1.952 |
| Sat 9/15 | 127 | East Carolina | +9 1.909 |
| 12:30 PM | 128 | Southern Mississippi | -9 2.000 |
| Sat 9/15 | 129 | California | +17 1.980 |
| 09:00 AM | 130 | Ohio State | -17 1.926 |
| Sat 9/15 | 131 | Texas | -10.5 1.962 |
| 06:15 PM | 132 | Mississippi | +10.5 1.943 |
| Sat 9/15 | 133 | Arizona State | +7.5 1.877 |
| 04:00 PM | 134 | Missouri | -7.5 2.030 |
| Sat 9/15 | 137 | North Carolina | +3.5 1.909 |
| 12:30 PM | 138 | Louisville | -3.5 2.000 |
| Sat 9/15 | 139 | Virginia | +10.5 1.917 |
| 12:30 PM | 140 | Georgia Tech | -10.5 1.990 |
| Sat 9/15 | 143 | Miami Ohio | +20.5 1.971 |
| 01:00 PM | 144 | Boise State | -20.5 1.935 |
| Sat 9/15 | 145 | TCU | -21 1.980 |
| 09:00 AM | 146 | Kansas | +21 1.926 |
| Sat 9/15 | 147 | Rice | +20.5 1.971 |
| 04:00 PM | 148 | Louisiana Tech | -20.5 1.935 |
| Sat 9/15 | 149 | Western Michigan | +2.5 1.909 |
| 09:00 AM | 150 | Minnesota U | -2.5 2.000 |
| Sat 9/15 | 151 | Bowling Green | +3.5 1.962 |
| 04:00 PM | 152 | Toledo | -3.5 1.943 |
| Sat 9/15 | 153 | UAB | +33.5 1.952 |
| 04:00 PM | 154 | South Carolina | -33.5 1.952 |
| Sat 9/15 | 155 | Ohio | -6.5 1.917 |
| 03:30 PM | 156 | Marshall | +6.5 1.990 |
| Sat 9/15 | 157 | New Mexico | +33.5 1.909 |
| 04:00 PM | 158 | Texas Tech | -33.5 2.000 |
| Sat 9/15 | 159 | Florida | +2.5 2.020 |
| 03:00 PM | 160 | Tennessee U | -2.5 1.885 |
| Sat 9/15 | 161 | Colorado State | +10.5 1.990 |
| 05:00 PM | 162 | San Jose State | -10.5 1.917 |
| Sat 9/15 | 163 | Utah State | +14 1.952 |
| 05:00 PM | 164 | Wisconsin | -14 1.952 |
| Sat 9/15 | 165 | Idaho | +42.5 1.952 |
| 05:00 PM | 166 | LSU | -42.5 1.952 |
| Sat 9/15 | 167 | Notre Dame | +5 1.935 |
| 05:00 PM | 168 | Michigan State | -5 1.971 |
| Sat 9/15 | 169 | Ball State | +2.5 1.952 |
| 05:00 PM | 170 | Indiana | -2.5 1.952 |
| Sat 9/15 | 171 | Colorado | +14 1.990 |
| 05:00 PM | 172 | Fresno State | -14 1.917 |
| Sat 9/15 | 173 | New Mexico State | +12.5 1.952 |
| 05:00 PM | 174 | UTEP | -12.5 1.952 |
| Sat 9/15 | 175 | Houston U | +17 2.000 |
| 07:30 PM | 176 | UCLA | -17 1.909 |
| Sat 9/15 | 177 | Florida Atlantic | +43 1.909 |
| 04:30 PM | 178 | Georgia | -43 2.000 |
| Sat 9/15 | 179 | Arkansas State | +24.5 1.909 |
| 09:00 AM | 180 | Nebraska | -24.5 2.000 |
| Sat 9/15 | 181 | South Alabama | +31.5 1.935 |
| 03:00 PM | 182 | NC State | -31.5 1.971 |
| Sat 9/15 | 183 | Florida Intl | +17 1.971 |
| 01:00 PM | 184 | Central Florida | -17 1.935 |
| Sat 9/15 | 185 | UL Lafayette | +22 1.952 |
| 09:00 AM | 186 | Oklahoma State | -22 1.952 |
| Sat 9/15 | 187 | North Texas | +28.5 1.935 |
| 04:00 PM | 188 | Kansas State | -28.5 1.971 |
| Sat 9/15 | 189 | Middle Tenn St | -3.5 1.980 |
| 04:00 PM | 190 | Memphis | +3.5 1.926 |
| Sat 9/15 | 191 | Western Kentucky | +7 1.952 |
| 04:00 PM | 192 | Kentucky | -7 1.952 |
| Sat 9/15 | 193 | Mississippi St | -16.5 1.952 |
| 04:00 PM | 194 | Troy | +16.5 1.952 |
| Sat 9/15 | 195 | Ul Monroe | +16 2.030 |
| 09:20 AM | 196 | Auburn | -16 1.877 |
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