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Here goes the Grandmaster! (game pending) Joe Duffy is 8-3 in football the last two days, 9-4 this week. Six NFL winners, a season high, including two Wise Guys led by Sunday Night Football AFC Game of the Year. Oh the SNF total. We have passed on virtually all prime-time NFL games this season. But this one is huge.  Get the picks now

Miami-New England

• Miami thinned at DE with Cameron Wake and Andre Branch both hurt
• Patriots WR Josh Gordon, limited but practicing
• Ryan Tannehill has a 121.8 QBR, not buying it
• New England third worse margin of cover team in NFL at 1-2 -11.8
• Teams laying at least six points despite winning percentage .500 point higher are a go-against of 27-21 (favors New England)
  • General rule of thumb, use oddsmakers knowledge against them
• Tom Brady 11-4 against the spread to Dolphins
• Home teams 11-1 against the spread series
• New England 1-2 -11.8, second worst in league

Lions-Cowboys

• Cowboys no weapons and one of the best of the lesser Cole Beasley is less than 100 percent
• LB Sean Lee is out
• Anti-splits angles 140-104, another 203-163 favoring Detroit
• Home team a combined 6-0 SU in the two teams games combined
• Cowboys second biggest UNDER team, under 3-0 at -10.2 points per game
• Dallas second worst points per play at .141
• Dallas under 11-1 home
• Cowboys 6-1 favorites
• Dallas under 3-0 by -10.2, second worst NFL

UNDER 43.5

Texans-Colts

• Colts QB Andrew Luck 23-6 against the spread off loss
• Texas 0-8 against the spread skid

Browns-Raiders

• Browns are 3-0 against the spread, but by +3.8 points per game, worst against the spread margin of any 3-0 against the spread team
• Baker Mayfield has breathed new life
• OT game, rare win, heartbreaking loss to Saints, now travel 2154 miles, tough spot for Browns
• Baker Mayfield makes his first start at QB for Browns
  • Last 10 QBs who were No. 1 overall picks have lost SU and against the spread in debut

Saints-NY Giants

• New Orleans No. 2 over team going over 2-1 at +17.3 points per game
• Saints twice given up 37 or more points
  • Last year’s defense was an aberration
• With Barkley and Beckham, Giants will enough weapons to put up points
• Home underdogs of win as road underdog 138-97 (Giants)
• Saints 15-5 against the spread road
• Saints over 2-1 by +17.3 points per game, second in NFL

Eagles-Titans

• Home team is a combined 6-0 in both teams games
• Anti-splits angle is 125-80 favoring road favorites Eagles
• Home underdogs of win as road underdog 138-97 (Titans)
• Eagles bet back RB Jay Ajayi
• Eagles WR Alshon Jeffrey questionable to make his debut
• Titans QB Marcus Mariota no longer on injury report
• Underdog covered 8-of-9 Eagles games

Bears-Buccaneers

• Winston or Fitzpatrick?
• Trubisky off two wins, likely come out flat
• Bears a one-point loss at Green Bay away from being undefeated
• Tampa second in NFL in points per play at .540

Ravens-Steelers

• Ravens second in offensive yards per point
• Ravens allow 4.7 passing yards per attempt teams normally getting 6.3
• Roethlisberger will throw short and safe passes, OVER number of completions (probably about 29)
• Ravens 8-1 divisional dog, 5-4 SU
• Baltimore 6-1 series including 4-0 Pittsburgh
• Ravens 2-1 against the spread with league leading 11.3 margin of cover

Bengals vs. Falcons

• Falcons RB Devonta Freeman is out
  • Ran for 865 or more yards each of the last three years

Bills vs. Packers

• WR Randall Cobb is questionable for Packers
  • 91 percent of Packers snaps this season
• Bills RB LeSean McCoy is probable
  • 16 carries for 61 yards this season
• GB QB Aaron Rogers 27-12-2 home

Jets vs. Jaguars

• Jaguars RB Leonard Fournette questionable
  • 9 carries for 41 yards

49ers vs. Chargers

• 49ers QB Jimmy Garoppolo is out for season
  • CJ Beathard gets start
• Chargers 4-13 home favorites of three or more, 8-9 SU

Seahawks vs. Cardinals

• Cards Josh Rosen gets start
• WR Larry Fitzgerald is questionable
• Seahawks top WR Doug Baldwin will play
• Led by DT Robert Nkemdiche, who is questionable, Arizona banged up on defense
• Arizona under 17-5 at home
• Arizona 1-2 with league worst -12.3 margin of cover
• Arizona under 3-0 by league high -10.7 points per game